4.00 Credits
Prerequisite(s): MICR 3450 and University Advanced Standing. Covers the structure, function, expression, and evolution of microbial genes and genomes, with an emphasis on bacteria. Examines microbial genome replication, the flow of information from DNA to functional RNAs and proteins, mechanisms for regulation of genome expression, and microbial gene organization including bacterial genomes, operons, plasmids, and mechanisms of horizontal gene transfer. Discusses experimental methods to construct, map, and examine mutations, measure gene expression, and genetically modify microbes. Examines DNA sequencing, analysis and annotation of microbial genomes.. Course fee of $62 for materials applies.